New CLARITY technique seems capable of leeching away lipids in the CNS while maintaining intact protein structure through a transparent matrix [cite source=’pubmed’]23575631[/cite]. The upshot is a way of turning the brain almost completely transparent, allowing intact imaging of proteins. This is pretty amazing stuff. Not clear if it is better/worse than SCALE, which was recently reported in Nature Neuroscience [cite source=’pubmed’]21878933[/cite].